Mediterranean Diet Good for Brain Health, Study Finds

Seafood, fruit, nuts are good for brain health as well as overall health, researchers say

Mediterranean Diet Good for Brain Health, Study Finds
Photo by Natasha Connell / Unsplash

You've heard it before: the Mediterranean Diet is good for you. Just about everybody has heard the news that a diet rich in seafood, fruit and nuts can help reduce the risk of heart attack, stroke and related diseases.

And now a new study says it may also reduce the risk of dementia by almost a quarter.

Experts at Newcastle University found that individuals who ate a Mediterranean-like diet had up to 23% lower risk for dementia than those who did not.

This research, published in BMC Medicine, is one of the biggest studies of its kind as previous studies have typically been limited to small sample sizes and low numbers of dementia cases.

“The good news from this study is that, even for those with higher genetic risk, having a better diet reduced the likelihood of developing dementia," said John Mathers, Professor of Human Nutrition at Newcastle.

“Although more research is needed in this area, this strengthens the public health message that we can all help to reduce our risk of dementia by eating a more Mediterranean-like diet,” Mathers said.

More than 60,000 people studied

Scientists analyzed data from 60,298 individuals from the UK Biobank, a large cohort including individuals from across the UK, who had completed a dietary assessment.

The study's authors scored individuals based on how closely their diet matched the key features of a Mediterranean one. The participants were followed for almost a decade, during which time there were 882 cases of dementia.

The authors considered each individual’s genetic risk for dementia by estimating what is known as their polygenic risk - a measure of all the different genes that are related to the risk of dementia.

The authors found there was no significant interaction between the polygenic risk for dementia and the associations between Mediterranean diet adherence. They say this may indicate that even for those with a higher genetic risk, having a better diet could reduce the likelihood of developing the condition.

This finding was not consistent across all the analyses and the authors propose further research is needed to assess the interaction between diet and genetics on dementia risk.

Brain health benefit

“The findings from this large population-based study underscore the long-term brain health benefits of consuming a Mediterranean diet, which is rich in fruits, vegetables, whole grains, and healthy fats," said Dr. Janice Ranson, at the University of Exeter, joint lead author on the paper.

“The protective effect of this diet against dementia was evident regardless of a person’s genetic risk, and so this is likely to be a beneficial lifestyle choice for people looking to make healthy dietary choices and reduce their risk of dementia.

“Future dementia prevention efforts could go beyond generic healthy diet advice and focus on supporting people to increase consumption of specific foods and nutrients that are essential for brain health,” she said.

The authors caution that their analysis is limited to individuals who self-reported their ethnic background as white, British or Irish, as genetic data was only available based on European ancestry, and that further research is needed in a range of populations to determine the potential benefit.